New Tube mill from IKA for grinding tablets

Sample preparation of pills with the Tube Mill control

Few products are tested for quality and composition as often and intensively as pharmaceuticals. Regulatory prescriptions as well as GMP and internal instructions require the frequent analysis of raw materials, intermediate and final products. Cross contamination has to be excluded.

Until now tables either had to be dissolved extensively or a purification process for the grinding had to be validated. This process is both time and personnel intensive.

With the IKA Tube Mill control and the respective single-use grinding chambers MT-40 ('Tubes') tablets can be assimilated to powder. For this purpose the tablets are placed in the tubes, sealed and put on the drive. Now the desired speed can be set, the duration of the experiment determined and and the grinding process started. Afterwards the cample can be removed for alaysis or stored directly in the labeled grinding chamber. The ingredients of the tablet can now be determined by methods such as HPLC, NIR spectronomy, gas chromatography or titrimetry.

Full Description:
The world’s first patented Tube Mill control is a batch mill with disposable grinding chamber. Eliminates possibility of cross-contamination and the effort of cleaning. The grinding chamber and cover are made of a transparent material so grinding tests can be observed at any time. The mill can be used for hard (Mohs hardness up to 5), dry and brittle materials. It is especially suitable for grinding seeds, such as corn and wheat. During development of the mill, particular emphasis was placed on security. The mill will only start when the hood is closed. When the grinding chamber is not inserted properly or not closed properly, the drive unit will display an error message and the drive will not start. During operation, the grinding chamber cannot be opened. The drive and the grinding chambers are secured with a labyrinth seal. No dust can escape from the chamber or penetrate the drive.

» Clearly arranged, multilingual OLED-display
» Timer, adjustable from 5 s to 3 min
» USB interface for control and documentation of all the parameters
» Interval operation available
» Infinitely variable speed from 5000 to 25000 rpm
» Various operating modes
» Adjustable safety speed
» Adjustable safety time
» Programmable and storable test conditions
» Error Code Display
» Reproducible test results
» Easy operation with touch keypad
» Dust proof sealed housing
» Quiet operation

» Download brochure (PDF)