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Glass disc and PTFE mesh for USP method 5 transdermal testing

Transdermal or patch testing is carried out using USP method 5 (paddle over disc) or USP method 6, the rotating cylinder.
With paddle over disc, the transdermal patch is placed between a glass disc and an inert PTFE mesh. This is placed at the bottom of the vessel, with the mesh facing upwards, under a rotating paddle.

Unlike dissolution testing, transdermal testing is carried out at 32°C to reflect the lower temperature of the skin. Other variables such as the height setting and sampling requirements are the same as dissolution testing.
This USP 5 apparatus is sold as a borosilicate watch glass with a PTFE 17 mesh, held together by PTFE clips. Patches up to 90mm in diameter can be tested. It is compatible with all brands of dissolution bath and conforms exactly to the USP specification

Part Number: APPFIVE-HR

Transdermal or patch testing is carried out using USP method 5 (paddle over disc) or USP method 6, the rotating cylinder. The rotating cylinder is very similar to USP method 1 (the rotating basket). With USP method 6 however, the basket assembly is replaced by a solid stainless steel cylinder.

The cylinder consists of two parts that fit together: the main shaft/cylinder assembly plus an extension. The extension is used when the transdermal patch requires a larger area. Click the picture for more details.
Unlike dissolution testing, transdermal testing is carried out at 32°C to reflect the lower temperature of the skin. Other variables such as the height setting and sampling requirements are the same as dissolution testing.
This USP 6 apparatus is compatible with all brands of dissolution bath and conforms exactly to the USP specification
Part Number: APPSIX-01-EX